Arizona Cardinals vs Houston Texans picks, predictions, odds for NFL Week 15 game Sunday

Cardinals offer fans no hope in embarrassing loss to Rams at home
Arizona Republic insiders break down the Cardinals’ loss to the Los Angeles Rams in Week 14.
The Arizona Cardinals and Houston Texans play on Sunday, Dec. 14, at the Texans’ NRG Stadium in a game on the NFL Week 15 schedule.
Which team will win the NFL Week 15 game?
Check out these NFL Week 15 picks and NFL Week 15 predictions for the game, which can be seen at 11 a.m. MST on FOX (stream with FUBO).
The Texans are a 9.5-point favorite over the Cardinals in NFL Week 15 odds for the game, courtesy of BetMGM Sportsbook.
Houston is -525 on the moneyline, while Arizona is +400. The over/under (point total) is set at 42.5 points.
NFL Week 15 picks: Falcons at Buccaneers | Browns at Bears | Ravens at Bengals | Cardinals at Texans | Jets at Jaguars | Chargers at Chiefs | Bills at Patriots | Commanders at Giants | Raiders at Eagles | Packers at Broncos | Lions at Rams | Panthers at Saints | Colts at Seahawks | Titans at 49ers | Vikings at Cowboys | Dolphins at Steelers | The Republic’s picks
Watch Cardinals at Texans live on FUBO (free trial)
Jeremy Cluff writes: “Can the Cardinals upset the Texans on the road? Not if they play as they did against the Rams in Week 14. Houston’s defense will force some turnovers on its way to handing Jonathan Gannon another loss.”
Bookies.com: Bet the Cardinals with the points vs Texans
Bill Speros writes: “Two NFL polar opposites meet in Houston. The Cardinals quit early and often in a 45-17 home loss to the Rams. Their playoff drought continues this season. The Texans, meanwhile, slayed the demon Sunday night in beating Kansas City 20-10. The Texans best-in-the-NFL defense (16 PPG & 266.3 YPG) handed Patrick Mahomes the worst outing of his career Sunday, forcing 3 interceptions. That avenged a tough playoff loss in K.C. last season. Arizona’s covered 7 of 8 as road underdogs and rides a 5-0 ATS streak against the NFC. The Texans defense emerges as the dominant force here and harass Jacoby Brissett all day. Meanwhile, C.J. Stroud mixes the run and pass, amassing double-digit play drives that devour chunks of clock. Don’t expect a blowout. Just a solid victory for the home team.”
The site’s formula predicts that the Texans will win the NFL Week 15 game against the Cardinals.
ESPN: Texans have a 71.2% chance to beat Cardinals on Sunday
The site gives the Cardinals a 28.6% shot at winning the NFL Week 15 game, with the remaining percentage accounting for a tie.
Dimers: Texans 25, Cardinals 18
It writes: “After extensive simulations, our model gives the Cardinals a win probability of 26%, while the Texans have a win probability of 74%.”
Sportsnaut: Houston Texans 20, Arizona Cardinals 13
Matt Johnson writes: “The Houston Texans are an example that an elite defense can win games on its own as long as the offense protects the football and can take advantage of short fields. Now that C.J. Stroud is back, Houston’s ceiling offensively is just much higher. With the Arizona Cardinals depleted by injuries offensively and weak in the trenches, the Texans should move one step closer to a playoff spot with a Week 15 victory.”
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Reach Jeremy Cluff at [email protected]. Follow him on X, formerly Twitter @Jeremy_Cluff.
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