Hampshire and Isle of Wight Constabulary said its neighbourhood policing team has had regular contact with businesses in Portswood.
“They have made near weekly visits to Ceno in recent months, but have not had any issues raised. We are also not aware of any reports of criminal damage,” it added.
In a statement, Southampton Stand up to Racism said residents had experienced “noise, intimidation and disturbance” during the anti-immigration gatherings.
“Police time and resources have been repeatedly diverted to manage alcohol-fuelled protests that brought tension into a residential area,” the statement said.
“This environment has consequences. Footfall drops. People stay away. Businesses suffer.”
A Home Office statement said: “We are furious at the level of illegal migrants and asylum hotels.
“This government will close every asylum hotel. Work is well under way, with more suitable sites being brought forward to ease pressure on communities and cut asylum costs.
“We are working closely with local authorities, property partners and across-government so that we can accelerate delivery.”
The Highfield House Hotel has also been contacted for comment.
