The Cincinnati Reds (24-23) and Philadelphia Phillies (24-23) open a 3-game series Monday in Philadelphia, Pennsylvania. First pitch from Citizens Bank Park is scheduled for 6:40 p.m. ET. Let’s analyze MLB odds around the Reds vs. Phillies odds and make our expert MLB picks and predictions for the best bets.
2025 season series: Tied 3-3 with the Phillies winning 2 of 3 at home
The Reds have lost 2 games in a row, 4 of their last 6, and 12 of their last 16. They lost the final game of their road series 10-3 against the Cleveland Guardians Sunday. SP Brady Singer (4 IP, 7 H, 5 ER, 1 BB, 6 K) allowed 3 home runs and the bullpen allowed another 3 HRs to the Guardians. The Cincinnati offense had 11 hits, but only was able to score 3 runs and left 8 runners on base.
The Phillies open a 6-game homestand after going 5-1 on their road trip, winning the final 4 games. They are 11-3 in their last 14 games. They shut out the Pittsburgh Pirates 6-0 for the second consecutive day on Sunday as Zack Wheeler (7 IP, 4 H, 0 ER, 1 BB, 8 K) outdueled Paul Skenes, and improved to 3-0 and dropped his ERA to 1.99. OF Bryce Harper hit his 12th home run, and 2B Bryson Stott drove in 3 runs with a 2-run double and a solo shot, his fourth of the season.
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Reds at Phillies projected starters
LHP Nick Lodolo vs. RHP Andrew Painter
Lodolo (0-1, 8.68 ERA) makes his third start. He has a 1.61 WHIP, 4 BB and 8 K in 9 1/3 innings.
- Last start: No-decision, 4 IP, 5 ER, 6 H, 3 BB, 6 K in 8-7 10-inning home loss to Washington Nationals Wednesday
- Career vs. Phillies: 1-1, 3.06 ERA (35 1/3 IP, 12 ER), 1.19 WHIP, 11.0 K/9 in 6 starts
- Making first road start of the season
Painter (1-4, 6.21 ERA) makes his eighth start and ninth career appearance. He has a 1.59 WHIP, 2.9 BB/9 and 8.1 K/9 in 37 2/3 innings.
- Last start: No-decision, 5 IP, 1 ER, 4 H, 1 BB, 4 K in 3-1 road loss to Boston Red Sox Wednesday
- 23-year-old rookie facing Reds for first time
- 2026 home splits: 1-2, 6.50 ERA (18 IP, 13 ER), 1.39 WHIP, 10.5 K/9 in 3 starts and a relief appearance
Reds at Phillies odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:25 a.m. ET.
- Moneyline (ML): Reds +105 (bet $100 to win $105) | Phillies -125 (bet $125 to win $100)
- Run line (RL)/Against the spread (ATS): Reds +1.5 (-185) | Phillies -1.5 (+150)
- Over/Under (O/U): 10 (O: -102 | U: -118)
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Reds at Phillies picks and predictions
Prediction
Phillies 7, Reds 4
While the Reds and Phillies have identical records, their recent play is very different. The Reds are 4-12 in their last 16 games, while the Phillies are 11-3 in their last 14.
Philly has allowed 3 or fewer runs in 7 of their last 8 games while the Reds have allowed 6 or more runs in 3 straight, and in 5 of their last 6.
BET PHILLIES (-125).
Five of the Reds’ last 6 losses have been by multiple runs. Nine of the Phillies’ last 11 wins have been by at least 2 runs.
Per Teamrankings.com, the Phillies are 7-15 ATS as home favorites, but 9 of their last 11 overall wins have also been covers.
BET PHILLIES -1.5 (+150).
Six of the Phillies’ last 7 games and 8 of their last 11 wins have not reached 10 total runs.
The Reds’ last 6 games have all had totals above 10 runs. Their last 7 losses have had double-digit totals.
BET OVER 10 (-102).
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