The Chicago Cubs (34-32) and Colorado Rockies (24-42) tussle in the Tuesday opener of a 3-game series in Denver, Colorado. The first pitch from Coors Field is slated for 8:40 p.m. ET. Let’s analyze MLB odds around the Cubs vs. Rockies odds and make our expert MLB picks and predictions for the best bets.
2025 season series: Cubs won 5-1
Chicago — which last season held the Rockies to just 21 runs across 6 meetings — arrives in Denver after a shaky 2-4 homestand followed by a Monday off day. The Cubs are just 5-16 since May 16; that stretch includes the club going just 2-10 at Wrigley Field.
Colorado, which was also off Monday, heads into this set looking to snap a 4-game losing streak. Among those 4 straight setbacks were 3 in a row to the Milwaukee Brewers over the weekend. Since May 19, the Rockies have gone 5-13 with a minus-56 run differential.
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Cubs at Rockies projected starters
RHP Colin Rea vs. RHP Tomoyuki Sugano
Rea (5-3, 4.59 ERA) is making his 11th start and 14th appearance. He owns a 1.35 WHIP, 3.1 BB/9 and 7.2 K/9 in 64 2/3 innings.
- Last start: No-decision, 5 1/3 IP, 2 ER, 4 H, 2 BB, 3 K in 5-4 loss vs. A’s Wednesday
- Career vs. Rockies (regular season): 1-0, 2.60 ERA (17 1/3 IP, 5 ER), 14 H, 7 BB, 13 K in 3 starts
- Clocked a 3.00 ERA through his first 4 starts, but owns a 5.53 ERA since
Sugano (5-4, 3.98 ERA) is making his 13th start. He has a 1.26 WHIP, 2.6 BB/9 and 5.1 K/9 in 63 1/3 innings.
- Last start: Win, 5 IP, 2 ER, 5 H, 2 BB, 5 K in 8-2 win at Los Angeles Angels last Tuesday
- Career vs. Cubs (regular season): 0-0, 5.40 ERA (5 IP, 3 ER), 5 H, 1 BB, 5 K in 1 start
Cubs at Rockies odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:21 p.m. ET.
- Moneyline (ML): Cubs -154 (bet $154 to win $100) | Rockies +130 (bet $100 to win $130)
- Run line (RL)/Against the spread (ATS): Cubs -1.5 (-102) | Rockies +1.5 (-118)
- Over/Under (O/U): 12.5 (O: -105 | U: -115)
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Cubs at Rockies picks and predictions
Prediction
Cubs 7, Rockies 6
Chicago is 6-1 across the last 7 series meetings.
Warm weather is expected for this one, and Sugano is more prone to yielding fly balls. The Colorado righty is a pitch-to-contact type who has yielded a lot of barreled-up contact.
The Cubs are just over-.500 with a scoring profile (4.59 runs per game, 4.55 RPG allowed) that would appear to back the winning rate. But a drill-down into the metrics reveals some helping regression due on both sides. For example, the Chicago offense has been hampered by a relatively low .283 batting average on balls in play. With runners in scoring position, the Cubs have slogged through a .273 BABIP.
The Rockies have been woeful at Coors Field, where they are just 6-16 since April 20.
CHICAGO (-154) is the edge side.
No interest; PASS.
The Over has cashed in 7 of Chicago’s last 10 road games, and the Over is 4-2 in the Cubs’ last half-dozen games at Coors Field. The Over has hit in 6 of Colorado’s last 7.
Peg both offenses as being more capable than what surface scoring averages currently show. Mix in one bad bullpen (Colorado owns a league-worst 5.30 ERA) and one overrated one (Chicago’s 3.56 ERA is colored by a .262 BABIP).
On a warm night at run-happy Coors, the OVER 12.5 (-105) is a leverage play.
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