What happened to Emari Demercado? Live injury updates for 49ers at Cardinals on Sunday 11/16/25

Ciaran Doyle provides the latest injury updates for Cardinals RB Emari Demercado after his injury vs. the 49ers.

In the second quarter of Sunday’s game vs. the 49ers, running back Emari Demercado injured his right foot/ankle area and went to the medical tent. After a short stint there, he headed back to the locker room. Demercado is now considered questionable to return with an ankle injury.

Before exiting, he rushed five times for eight yards. He also caught two of his three targets for 12 yards. If Demercado doesn’t return, expect Zonovan Knight to take over the bulk of the carries for Arizona. Before today’s game, he carried the ball 26 times for 233 yards this season while averaging 9.0 yards per carry.

Stay tuned to DK Network for live updates on his injury.