Cavaliers vs. Pistons odds, line: Proven model reveals picks for NBA Eastern Conference semifinal Game 7 matchup on Sunday, May 17

A trip to the NBA Eastern Conference finals will be on the line when the fourth-seeded Cleveland Cavaliers battle the top-seeded Detroit Pistons on Sunday night. Detroit forced a Game 7 with a 115-94 win at Cleveland on Friday. The Cavaliers (52-30), who finished second in the Central Division, are looking to reach the Eastern Conference finals for the first time since 2017-18. The Pistons (60-22), who won the Central Division, are looking to reach the Eastern Conference finals for the first time since 2007-08. Duncan Robinson (back) and Caris LeVert (heel) are questionable for Detroit.

Tip-off from Little Caesars Arena in Detroit is set for 8 p.m. ET. The Cavaliers lead the all-time postseason series 18-9. The Pistons are a 4.5-point favorite in the latest Cavaliers vs. Pistons odds from FanDuel Sportsbook, while the over/under for total points scored is 205.5. The Pistons are at -190 on the money line (risk $190 to win $100), with the Cavs the +159 underdogs (risk $100 to win $159).

Before making any Cavaliers vs. Pistons picks, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the second week of the second round of the 2026 NBA playoffs on a sizzling 26-9 roll (74%) on top-rated NBA spread picks this season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen HUGE returns!

The model has simulated Cavaliers vs. Pistons 10,000 times and the results are in. The model is going Over on the point total, and it also says one side of the spread hits well over 60% of the time!