Marcus Thuram and Ange-Yoan Bonny start for Inter in the trip to Borussia Dortmund, facing Serhou Guirassy and Jobe Bellingham.
It kicks off at the Westfalenstadion at 20.00 GMT (21.00 CET).
You can follow all the build-up and action as it happens from this game, Napoli-Chelsea, Monaco-Juventus and Union Saint-Gilloise-Atalanta on the Liveblog.
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All the matches are played simultaneously in the final round of the league phase, as Inter slipped out of the top eight and must win to have any chance of avoiding the play-offs.
UDINE, ITALY – JANUARY 17: Cristian Chivu, manager of FC Internazionale, during the post-match press conference at the Serie A match between Udinese Calcio and FC Internazionale at Stadio Friuli on January 17, 2026 in Udine, Italy. (Photo by Timothy Rogers/Getty Images)
Denzel Dumfries, Hakan Calhanoglu and Nicolò Barella are injured, with Lautaro Martinez initially rested, also as he is on a yellow card.
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Instead, Bonny steps in to partner Thuram, with Francesco Pio Esposito also ready to come off the bench.
Luis Henrique is confirmed on the right wing, with Petar Sucic and Piotr Zielinski in midfield together.
Inter had started the Champions League so well winning the opening four matches, but have now lost three on the bounce.
MILAN, ITALY – JANUARY 04: Piotr Zielinski of FC Internazionale Milano celebrates scoring his team’s first goal with teammates during the Serie A match between FC Internazionale and Bologna FC 1909 at Giuseppe Meazza Stadium on January 04, 2026 in Milan, Italy. (Photo by Marco Luzzani/Getty Images)
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Borussia Dortmund are in 16th place, one point behind Inter going into this final game.
They are forced into some changes, as Daniel Svensson is suspended, while Marcel Sabitzer and Niklas Sule are injured.
A late addition to the absentee list is defender Waldemar Anton, who is suffering from an illness, so Ramy Bensebaini drops into a deeper role.
Guirassy leads the attack, with support from Jobe Bellingham, but Karim Adeyemi is benched.
CINCINNATI, OHIO – JUNE 21: Serhou Guirassy #9 of Borussia Dortmund celebrates after scoring a goal during the FIFA Club World Cup 2025 group F match between Mamelodi Sundowns FC and Borussia Dortmund at TQL Stadium on June 21, 2025 in Cincinnati, Ohio. (Photo by Michael Reaves/Getty Images)
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Borussia Dortmund vs. Inter line-ups
Borussia Dortmund: Kobel; Emre Can, Schlotterbeck, Mane; Ryerson, Bellingham, Nmecha, Bensebaini; Beier, Silva; Guirassy
Inter: Sommer; Bisseck, Acerbi, Akanji; Luis Henrique, Sucic, Zielinski, Mkhitaryan, Dimarco; Thuram, Bonny
Ref: Kovacs (ROU)
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Champions League line-ups: Union Saint-Gilloise vs. Atalanta
