Mazatlan vs. Guadalajara prediction, odds, Liga MX picks [2/6/2026]

Mazatlan and Guadalajara are scheduled to meet in the Liga MX playoffs at Estadio El Encanto on Friday, with kickoff at 10:06 PM ET.

Based on the latest simulations, Dimers’ proven Liga MX model predicts Guadalajara as the most likely winner of the Mazatlan vs. Guadalajara game.

This article offers an expanded analysis of Friday’s matchup, including best bets and picks.

Mazatlan vs. Guadalajara prediction: Who will win?

Using innovative machine learning and data, we have simulated the outcome of Friday’s Liga MX matchup between Mazatlan and Guadalajara 10,000 times as part of our Liga MX predictions coverage.

Our famous predictive model suggests an 18.4% chance of Mazatlan winning, a 57.6% chance for Guadalajara, and a 24.1% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 54% chance of staying under, according to our model.

Mazatlan vs. Guadalajara odds

We have researched the best Liga MX odds in America for this game, which are listed here:

Moneyline

Mazatlan
Guadalajara
Draw

+650
-235
+410

Total Goals

Over 2.5
Under 2.5

-160
+134

All odds are correct at the time of publication and are subject to change.

Mazatlan vs. Guadalajara picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: