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Sean Strickland vs. Anthony Hernandez: Odds, full fight preview and prediction | UFC Houston

Ultimate Fighting Championship (UFC) Middleweight contenders Sean Strickland vs. Anthony Hernandez will clash TONIGHT (Sat., Feb. 21, 2026) inside Toyota Center in Houston, Texas, for UFC Houston.

Where does Strickland stand in 2026?

It’s a difficult question to answer until the conclusion of tonight’s main event. The former champion only competed once last year, a one-sided loss to then-kingpin, Dricus du Plessis. Returning to the win column here would push Strickland right back into the limelight as a possible title threat to either Khamzat Chimaev or Nassourdine Imavov, whereas a loss would send him plummeting down the ranks.

Hernandez, meanwhile, rides an eight-fight win streak into his third main event booking. “Fluffy” has been wildly dominant while climbing the Middleweight ladder, making skilled opposition look downright miserable while locked in the cage with him. If he can put Strickland in similar agony, there’s no doubt Hernandez his earned his shot at UFC gold.

Let’s take a closer look at the betting odds and strategic keys for each athlete:

LAS VEGAS, NEVADA – AUGUST 09: (L-R) Roman Dolidze of Georgia punches Anthony Hernandez in a middleweight fight during the UFC Fight Night event at UFC APEX on August 09, 2025 in Las Vegas, Nevada. (Photo by Jeff Bottari/Zuffa LLC)

Strickland vs. Hernandez Betting Odds

  • Sean Strickland victory: +235
  • Sean Strickland via TKO/KO/DQ: +750
  • Sean Strickland via submission: +4000
  • Sean Strickland via decision: +400
  • Anthony Hernandez victory: -300
  • Anthony Hernandez via TKO/KO/DQ: +700
  • Anthony Hernandez via submission: +290
  • Anthony Hernandez via decision: +135
  • Odds via FanDuel Sportsbook

SYDNEY, AUSTRALIA – FEBRUARY 09: Sean Strickland reacts after a unanimous-decision loss against Dricus Du Plessis of South Africa in the UFC middleweight championship fight during the UFC 312 event at Qudos Bank Arena on February 09, 2025 in Sydney, Australia. (Photo by Jeff Bottari/Zuffa LLC)

Strickland’s style is exceptionally annoying to deal with and built off his comfort in exchanges, a trait many mixed martial arts (MMA) fighters (even great ones) lack. He maintains a steady pressure and presence, always staying in his opponent’s face and picking at them with jabs, teeps and counter punches. Historically, he’s quite hard to take down as well, but he hasn’t been tested by anyone quite like Hernandez is many years.

Though their strategies differ, this is a collision of men who like to bully and break their opponents. Strickland may not “go to war” as often as he promises in pre-fight talk, but he does poke and prod at his opponents until they’d prefer to be doing just about anything else. Like “Fluffy,” he does his best work on the front foot when dictating the exchanges.

It’s important that he doesn’t back up here and let Hernandez shoot easy takedowns. Instead, I’d like to see Strickland establishing his teep to the belly early given Hernandez’s history of getting hurt by body shots, and that’s just a great anti-wrestler strike regardless. If Strickland can give Hernandez a reason to hesitate on the outside, he can build success and start forcing him to take backwards steps.

With both men, their success tends to snowball, so taking the initiative early will be pivotal.

Hernandez is the meanest mat mauler since Khabib Nurmagomedov. I’m not say he’s as good as “The Eagle” or anything, but there’s a certain cruelty and nastiness in how Hernandez delivers ground strikes while mugging his opposition that puts him in a rarified class of ground fighters.

Pretty much everybody and their mother expects the teep to be something of an issue — or at least Strickland’s best path to success — given Hernandez’s history of getting hurt by body shots. Therefore, it feels obvious to say Hernandez should come equipped with tools to answer. For example, I would love to see him looking to parry the kick by, which would allow Hernandez to counter with low kicks, punches, or even a takedown entry.

Discouraging Strickland from throwing the kick would certainly be helpful in the long run.

Generally, I don’t believe Hernandez needs to rush his takedowns. He should be shooting often, but he doesn’t need to be desperate. Hernandez has variety in his kickboxing, good offense from a multitude of ranges. Like du Plessis, he should use his full arsenal to beat up the legs with kicks, match Strickland’s volume in the pocket, and look for clubbing close range blows when in the clinch.

Strickland has a habit of going reactive in the face of output, and Hernandez can encourage him into that statement with constant, unpredictable offense. The takedown is still the end goal, but it will come more easily if Strickland is worried about kicks, elbows and punches, too.

LAS VEGAS, NEVADA – AUGUST 09: Anthony Hernandez reacts after a submission victory against Roman Dolidze of Georgia in a middleweight fight during the UFC Fight Night event at UFC APEX on August 09, 2025 in Las Vegas, Nevada. (Photo by Jeff Bottari/Zuffa LLC)

Hernandez vs. Strickland Prediction

In this battle of bullies, I like the man with more tools.

Strickland is in his 18th year as a professional fighter — we really shouldn’t expect anything different from “Tarzan.” He’s going to jab and teep at a consistent rate, and I expect “Fluffy” to have an answer. I don’t expect it will be easy necessarily, but Hernandez will keep up with Strickland’s standup to a reasonable degree and therefore even a bit of wrestling success will be enough to turn the tide.

If Strickland starts falling behind on the scorecards, is anybody expecting him to ramp it up and score the finish?

Prediction: Hernandez via decision

To checkout UFC Houston’s final fight card and bout order click here.

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