News US
Kentucky vs Santa Clara predictions, picks, odds for NCAA Tournament First Round

The First Round of the men’s 2026 NCAA Tournament continues Friday with No. 7 Kentucky vs. No. 10 Santa Clara on the 16-game schedule.
Here is Friday’s full first-round March Madness schedule and expert picks from reporters across the USA TODAY Sports Network.
USA TODAY Sports has a team of journalists covering the men’s NCAA Tournament to keep you up to date with every point scored, rebound grabbed and game won in the 68-team tournament.
Join the USA TODAY $1 million Bracket Challenge
No. 7 Kentucky vs No. 10 Santa Clara prediction
- Ehsan Kassim: Santa Clara
- John Leuzzi: Santa Clara
- Craig Meyer: Kentucky
- Jordan Mendoza: Santa Clara
No. 7 Kentucky vs No. 10 Santa Clara odds
- Opening Moneyline: Kentucky (-162)
- Opening Spread: Kentucky (-2.5)
- Opening Total: 161.5
How to Watch Kentucky vs Santa Clara today
No. 7 Kentucky takes on No. 10 Santa Clara at Enterprise Center on March 20 at 12:15 p.m.. The game is airing on CBS.
Stream March Madness on Fubo
2026 Men’s March Madness full schedule
See the schedule, live scores and results for all of today’s NCAA Tournament action here.
- March 17-18: First Four
- March 19-20: First Round
- March 21-22: Second Round
- March 26-27: Sweet 16
- March 28-29: Elite 8
- April 4: Final Four
- April 6: National Championship



