2025 NFL Week 7 Falcons vs. 49ers line, odds: Expert reveals pick for Sunday Night Football matchup
The Atlanta Falcons look to win their third game in a row when they take on the injury-hampered San Francisco 49ers on Sunday Night Football. San Francisco lost linebacker Fred Warner (ankle), who had to undergo season-ending surgery, and has had a growing list of injured players that have been going in and out of its starting lineup. The Falcons (3-2), who are second in the NFC South, are 1-1 on the road this season. The 49ers (4-2), who are tied for first with Seattle and the Los Angeles Rams in the NFC West, are 1-1 on their home field. San Francisco quarterback Brock Purdy (toe) is out, but George Kittle (hamstring) is active for the first time since Week 1. Both teams have three against-the-spread victories on the season.
Kickoff from Levi’s Stadium in Santa Clara, Calif., is set for 8:20 p.m. ET. The 49ers lead the all-time series 48-33-1, but the Falcons have won three of the last four meetings. San Francisco is a 1-point favorite in the latest Falcons vs. 49ers odds, while the over/under for total points scored is 46.5. San Fran is at -113 on the money line (risk $113 to win $100), while Atlanta is a -106 underdog (risk $106 to win $100).
Before making any Falcons vs. 49ers bets or predictions, make sure you check out what SportsLine NFL expert Micah Roberts has to say, given his mastery of picks in games involving the 49ers.
Micah Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos’ book director. Most importantly, Roberts has a read on the pulse of the 49ers. He is 18-4 (+1360) on his last 22 against-the-spread picks in games involving San Francisco! Anybody following could be WAY UP!
Now, Roberts has locked in another confident against-the-spread pick for Falcons vs. 49ers.
We can tell you he’s leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.
