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Guardians vs Yankees Prediction, Picks & Odds for Today’s MLB Game


Shawn Krest
• Betting Analyst

20+ years betting experience

Updated:
Jun 4, 2026 , 10:32 AM ET

• 4 min read

Jose Ramirez and the Guardians upend Judge-less Yankees.

Photo By – Reuters Connect. Jose Ramirez of the Cleveland Guardians MLB

The Yankees will try to find a way to score runs without Aaron Judge as they try to avoid a sweep against the visiting Guardians.

Cleveland has beaten Cam Schlittler and Gerrit Cole the last two days, so Carlos Rodon shouldn’t scare them.

While the Yankees have struggled to hit, Cleveland has been raking, which is why my Guardians vs. Yankees predictions and MLB picks have the Guardians finishing off the sweep.

Who will win Guardians vs Yankees today: Guardians (+150)

Aaron Judge will miss his third straight game, and the New York Yankees aren’t the same team without him. In the last five games without Judge, dating to last year, New York is 1-4, .200 without Judge, and averages 3.6 runs a game, compared to 5.2 runs and a .586 win percentage with him.

It’s a surprise they’re such heavy favorites, even with Carlos Rodon going. I’d take the Cleveland Guardians moneyline to +120.

The Guardians have scored 14 runs in the first two games, with Jose Ramirez and Kyle Manzardo destroying Yankee pitching. The pair is 11-for-17 in the series with 6 RBIs, 5 doubles, and 2 homers.

COVERS INTEL: The numbers say Carlos Rodon feels healthy. He’s added 1.5 mph to his sinker and is throwing both that and his four-seamer more often. Hitters are hitting .167 against the sinker, 90 points lower than last year, and .091 against the four-seam, a drop of 130 points.

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Guardians vs Yankees Over/Under pick: Under 8.5 (-104)

Rodon is making his fifth start of the year after missing the start with an injury. He’s in the top 10% in MLB in avoiding hard-hit balls and inducing grounders. Prior to the offensive explosion against New York in this series, the Guardians had gone 12 straight games scoring fewer than five runs.

Slade Cecconi starts for the Guardians. After a rough start to the season, he’s settled down, throwing a cutter instead of his slider. He’s allowed three runs or fewer in the last five starts, with the Guardians winning four of them. The Under seems like a good deal until at least -115 to -120.

Shawn Krest’s 2026 Transparency Record

  • ML/RL bets: 19-22, -1..79 units
  • Over/Under bets: 22-23, -2.51 units

Guardians vs Yankees odds

  • Moneyline: Guardians +150 | Yankees -156
  • Run line: Guardians +1.5 (-133) | Yankees -1.5 (+127)
  • Over/Under: Over 8.5 | Under 8.5

Guardians vs Yankees trend

The Cleveland Guardians have hit the Moneyline in 29 of their last 45 away games (+19.75 Units / 41% ROI). Find more MLB betting trends for Guardians vs. Yankees.

How to watch Guardians vs Yankees and game info

Location
Yankee Stadium, Bronx, NY

Date
Thursday, June 4, 2026

First pitch
1:35 p.m. ET

TV
CleGuardians.TV, YES

Guardians starting pitcher
Slade Cecconi
(3-5, 5.25 ERA)

Yankees starting pitcher
Carlos Rodon
(1-2, 3.32 ERA)

Guardians vs Yankees latest injuries

Guardians vs Yankees weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Since quitting his job as bank assistant vice-president in 2000, Shawn has covered Final Fours, Super Bowls, World Series games and title fights in boxing and UFC. His work has appeared on ESPN, MLB.com, Sports Illustrated and dozens of other outlets. His book, Baseball Meat Market was published in 2018. He lives in North Carolina with his dog Toby, eight turtles, and wife.

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