Englishman Christian Burgess is among those who start for Union Saint-Gilloise.
Union Saint-Gilloise XI: Scherpen, Mac Allister, Burgess, Leysen Khalaili, Zorgane, Van De Perre, Niang, Ait El Hadj, Rodriguez, David
Substitutes: Chambaere, Berradi, Patris, Sykes, Boufal, Giger Schoofs, Smith, Rasmussen, Barry
Newcastle United head coach Eddie Howe has made two changes to his side.
Kieran Trippier and Anthony Elanga have come in for Tino Livramento, who is set for a spell on the sidelines, and Jacob Murphy.
Newcastle XI: Pope, Trippier, Thiaw, Botman, Burn, Guimaraes, Tonali, Joelinton, Elanga, Gordon, Woltemade
Substitutes: Ramsdale, Thompson, Hall, Schar, Barnes, Krafth, Osula, J Murphy, Willock, A Murphy, Miley
