Yankees vs Guardians Prediction, Picks & Best Bets for Today’s MLB Game

Updated:
Jun 10, 2026 , 11:41 AM ET
• 4 min read
The Yankees shouldn’t be an underdog as they go for the series sweep vs. the Guardians, per our MLB expert.
Photo By – Reuters Connect. New York Yankees starting pitcher Carlos Rodon.
The New York Yankees go for the series sweep vs. the Cleveland Guardians this afternoon in a finale that pits Carlos Rodon against rookie Parker Messick.
Rodon owns a career 2.54 ERA in 24 appearances against the Guardians, and the bigger swing factor is a Cleveland bullpen that’s been used extensively in recent games.
Here are my Yankees vs. Guardians predictions and MLB picks for Wednesday, June 10.
Who will win Yankees vs Guardians today: Yankees moneyline (+100)
Carlos Rodon is an elite hard-hit suppressor with a ground-ball rate in the Top 80th percentile of baseball and a hard-hit rate that lands the same. I fully expect him to lean on that strength today.
Furthermore, there’s not much pop in this Cleveland Guardians lineup outside Jose Ramirez, best indicated by its second-to-last barrel rating, which means Rodon’s soft-contact profile gets stronger.
While I like Parker Messick a great deal, the game tilts once he exits. With the Guardians’ bullpen overextended, manager Stephen Vogt is forced to lean on non-premium arms.
Take the New York Yankees down to -115.
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Yankees vs Guardians Over/Under pick: Over 7.5 (-122)
The exhausted Cleveland bullpen carries roughly four innings behind Messick today, and Carlos Rodon walks 15.4% of hitters in 2026, ranking in the bottom third percentile.
While I expect Rodon to have a good day, it’s unlikely to come without giving up a few runs.
On the other side, the Yankees will make hay later in the game against a few bullpen arms that have hard-hit issues. Play to 8.
Chris Hatfield’s 2026 Transparency Record
- ML/RL bets: 28-23, +4.71 units
- Over/Under bets: 31-20, +13.87 units
Yankees vs Guardians odds
- Moneyline: Yankees +100 | Guardians -115
- Run line: Yankees +1.5 | Guardians -1.5
- Over/Under: Over 7.5 | Under 7.5
Yankees vs Guardians trend
The Yankees have covered the first five innings run line in 30 of their last 50 road games for +7.80 units and a 13% ROI.
How to watch Yankees vs Guardians and game info
Location
Progressive Field, Cleveland, OH
Date
Wednesday, June 10, 2026
First pitch
1:10 p.m. ET
TV
YES, Guardians.TV
Yankees starting pitcher
Carlos Rodon
(1-2, 2.88 ERA)
Guardians starting pitcher
Parker Messick
(6-2, 2.40 ERA)
Yankees vs Guardians latest injuries
Yankees vs Guardians weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Chris has always had a passion for three things: solving problems, sports, and writing. It’s no wonder then that he found himself attracted to the sports betting industry. You can find Chris betting every day. Whether it’s shot prop markets in Champions League Soccer qualifiers or NBA Summer League, he has no offseason. As an EV+ bettor, he especially values the insight gained through a data-driven approach.
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