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What channel is Rams vs. 49ers on? Schedule, time, live stream to watch NFL ‘Thursday Night Football’ in Week 5

The Rams and 49ers will face off in a pivotal Week 5 showdown Thursday night.

The winner of this game will take sole possession at the top of the NFC West, as both teams enter the game 3-1.

Los Angeles is coming off a big win in Week 4 thanks to an 88-yard touchdown strike from Matthew Stafford to Tutu Atwell late in the game. San Francisco couldn’t muster a fourth-quarter comeback against Jacksonville and lost its first game of the 2025 season.

The Rams also enter the game very healthy; the team will have its full complement of players, including Stafford, receivers Davante Adams and Puka Nacua, running back Kyren Williams and their entire defensive line.

The 49ers, on the other hand, are very injured. Quarterback Brock Purdy and receiver Ricky Pearsall are both questionable with injuries; receiver Jauan Jennings is still hurt; and tight end George Kittle is still on injured reserve. A lot will be riding on star running back Christian McCaffrey in this one.

Here is everything you need to know about Rams vs. 49ers, including TV and streaming options for Thursday’s game.

What channel is Rams vs. 49ers on?

The Rams vs. 49ers game will air exclusively on Prime Video.

Al Michaels (play-by-play) and Kirk Herbstreit (analyst) will be on the call with Kaylee Hartung reporting from the sidelines.

Rams vs. 49ers start time

  • Date: Thursday, Oct. 2
  • Time: 8:15 p.m. ET

Rams vs. 49ers will kick off at 8:15 p.m. ET on Thursday, Oct. 2. The game will be played at SoFi Stadium in Los Angeles.

Rams vs. 49ers radio station

  • Radio station: SiriusXM channels 225 (Rams broadcast), 226 (49ers broadcast)

You can listen to Rams vs. 49ers live on SiriusXM. Coverage will be available on channels 225 (Rams broadcast) and 226 (49ers broadcast).

New subscribers get their first month of SiriusXM for free. Listen to every NFL game live, plus college football, MLB, NBA, NHL, NASCAR and more. Stay updated with all the news and analysis from SiriusXM NFL Radio and other sport-specific channels.

Rams 2025 schedule

Here’s the full 2025 schedule for Los Angeles.

DateGameTimeTV/Live streamSept. 7Rams 14, Texans 9——Sept. 14Rams 33, Titans 19——Sept. 21Eagles 33, Rams 26——Sept. 28Rams 27, Colts 20——Oct. 2vs. 49ers8:15 p.m.Prime VideoOct. 12at Ravens1 p.m.FOXOct. 19vs. Jaguars9:30 a.m.NFL Network, NFL+Nov. 2vs. Saints4:05 p.m.FOXNov. 9at 49ers4:25 p.m.FOXNov. 16vs. Seahawks4:05 p.m.FOXNov. 23vs. Buccaneers8:20 p.m.NBCNov. 30at Panthers1 p.m.FOXDec. 7at Cardinals4:25 p.m.FOXDec. 14vs. Lions4:25 p.m.FOXDec. 18at Seahawks8:15 p.m.Prime VideoDec. 29at Falcons8:15 p.m.TBDTBDvs. CardinalsTBDTBD

49ers 2025 schedule

Here’s the full 2025 schedule for San Francisco.

DateGameTimeTV/Live streamSept. 749ers 17, Seahawks 13——Sept. 1449ers 26, Saints 21——Sept. 2149ers 16, Cardinals 15——Sept. 28Jaguars 26, 49ers 21——Oct. 2at Rams8:15 p.m.Prime VideoOct. 12at Buccaneers1 p.m.CBSOct. 19vs. Falcons8:20 p.m.NBCOct. 26at Texans1 p.m.FOXNov. 2at Giants1 p.m.CBSNov. 9vs. Rams4:25 p.m.FOXNov. 16at Cardinals4:05 p.m.FOXNov. 24vs. Panthers8:15 p.m.—Nov. 30at Browns1 p.m.CBSDec. 14vs. Titans4:25 p.m.FOXDec. 22at Colts8:15 p.m.—Dec. 28vs. Bears8:20 p.m.NBCTBDvs. SeahawksTBD—

NFL Week 5 schedule

Thursday, October 2, 2025

GameTimeTV/Live streamSan Francisco at Los Angeles8:15 p.m.Prime Video

Sunday, October 5, 2025

GameTimeTV/Live streamMinnesota at Cleveland9:30 a.m.NFL Net / NFL+Las Vegas at Indianapolis1 p.m.FOX, FuboNew York at New Orleans1 p.m.CBSDallas at New York1 p.m.FOXDenver at Philadelphia1 p.m.CBSMiami at Carolina1 p.m.FOXHouston at Baltimore1 p.m.CBSTennessee at Arizona4:05 p.m.CBSTampa Bay at Seattle4:05 p.m.CBSDetroit at Cincinnati4:25 p.m.FOXWashington at Los Angeles4:25 p.m.FOXNew England at Buffalo8:20 p.m.NBC

Monday, October 6, 2025

GameTimeTV/Live streamKansas City at Jacksonville8:15 p.m.ABC, ESPN

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