College football Week 7 straight-up picks
Week 7 picks include Indiana-Oregon, Alabama-Missouri, Texas-Oklahoma and more.
Two storied programs will meet in Week 7 with No. 15 Michigan making the trip out West to face Southern California.
The Wolverines have had a solid start to Big Ten play with two straight victories, the latest coming in a 24-10 win over Wisconsin. Freshman quarterback Bryce Underwood had one of his best performances of his young career, giving Michigan plenty of optimism on the road.
Southern California had a week off to recover from the heartbreaking loss to Illinois, the first conference defeat for the Trojans. Now, they’ll try to exact revenge on a team they lost to last season, and get back to winning ways in what is the most important stretch of the season for Lincoln Riley and company.
Stream Michigan vs. USC on Fubo (free trial)
What channel is Michigan vs USC on today?
USC and Michigan will air nationally on NBC in Week 7 of the 2025 college football season from Los Angeles Memorial Coliseum in Los Angeles. Noah Eagle (play-by-play) and Todd Blackledge (analyst) will call the game from the booth while Kathryn Tappen will serve as the sideline reporter.
Streaming options include Peacock ― NBC’s streaming platform ― and Fubo, the latter of which offers a free trial to potential subscribers.
Stream Michigan vs. USC on Peacock
Michigan vs USC time today
- Date: Saturday, Oct. 11
- Start time: 7:30 p.m. ET
The game between the Wolverines and Trojans is scheduled to kick off at 7:30 p.m. ET on Oct. 11 from Los Angeles Memorial Coliseum in Los Angeles, California.
Michigan vs USC predictions, picks, odds
Odds courtesy of BetMGM as of Tuesday, Oct. 7.
- Spread: USC (-2.5)
- Over/under: 56.5
- Moneyline: USC (-130) ∣ Michigan (+105)
Prediction: USC 24, Michigan 20
The Trojan offense isn’t as explosive, but the defense steps up to make life difficult for Bryce Underwood to pick up a signature win at home.
