What we’re hearing on the Eagles: This matchup features two of the NFL’s most prolific rushing QBs in Jalen Hurts and Josh Allen. Hurts has been more selective with his feet this season and is on pace for career lows for rushing attempts and yards since taking over as the full-time starter in 2021. He has stepped it up of late, though, rushing 14 times for 79 yards over the past two games. Expect that trend to continue as the stakes rise around playoff time. — Tim McManus
What we’re hearing on the Bills: RB James Cook III has the lead in the battle for the rushing title (1,532) over the Colts’ Jonathan Taylor (1,489), and continuing his success on the ground could go a long way against the defending Super Bowl champions. The Eagles have allowed 123.5 rushing yards per game (21st) and given up first downs on 27.6% of rushes (27th). “[Cook] had some big games last year, but the look in his eye each week, the intensity that he shows up with, it’s really been influential on our whole football team,” coach Sean McDermott said. “Guys see that. That’s kind of a little bit unique for a running back position player to have that type of impact on the whole team.” — Alaina Getzenberg
Stat to know: In 2023’s Week 12 battle between these two teams, Hurts and Allen both finished with multiple passing touchdowns and multiple rushing touchdowns, marking the first game in NFL history where opposing players accomplished that feat, according to the Elias Sports Bureau. — ESPN Research
Bold prediction: Allen will rush for at least 60 yards. The Bills receivers are going to be outmatched by the Eagles in this game, so it could fall even more than usual on the shoulders of Allen to generate production. — Walder
What’s at stake: The Eagles have clinched a playoff berth and the NFC East. If the Bills lose, they will be out of contention for the AFC East title, but have still clinched a playoff berth. See Playoff Machine. — ESPN Research
Fantasy nugget: The Bills’ defensive front has allowed the third-most rushing yards per game and now has to deal with Eagles RB Saquon Barkley, who has logged at least 20 touches and 17 fantasy points in three consecutive games. Barkley remains the focal point of a Philadelphia offense that’s finally settling into an identity with the playoffs approaching. See Week 17 rankings. — Moody
Betting nugget: The Eagles are 5-0 outright as underdogs since the start of last season, including playoffs (4-0 in regular season). Read more. — ESPN Research
Maldonado’s pick: Eagles 19, Bills 16
Moody’s pick: Bills 28, Eagles 24
Walder’s pick: Bills 24, Eagles 21
FPI prediction: BUF, 50.3% (by an average of 0.0 points)
