NFL Overreactions Week 4: Cowboys-Packers tie, Dart shines
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Sports Seriously
For the second consecutive week, “Thursday Night Football” will feature a battle of NFC West teams that will briefly catapult one squad into first place.
The San Francisco 49ers (3-1) are traveling to southern California to take on the Los Angeles Rams (3-1) in a matchup between two playoff hopefuls.
The Rams enter Thursday’s game as significant favorites. Matthew Stafford has looked healthy through four weeks, despite dealing with a back injury, while Puka Nacua and Davante Adams have emerged as one of the NFL’s best receiver duos over their first month together.
Meanwhile, the 49ers haven’t had consistency on offense. Brock Purdy (toe) and George Kittle (hamstring) have missed time due to injuries while Jauan Jennings (ankle/ribs) and Ricky Pearsall (knee) are also banged up entering Week 5. Christian McCaffrey has enjoyed a renaissance after an injury-plagued 2024 season, but he will be among the last skill position weapons standing for San Francisco during Thursday’s contest.
Will San Francisco’s offense have enough talent available to challenge a young, improving Rams defense? Here’s what to know about the Rams vs. 49ers “Thursday Night Football” matchup for NFL Week 5.
What time does Rams-49ers NFL game start?
The Rams vs. 49ers game will kick off at 8:15 p.m. ET on Thursday, Oct. 2. The game will be played at SoFi Stadium in Inglewood, Calif. and will mark the second consecutive week NFC West teams have squared off on “Thursday Night Football” after the Arizona Cardinals hosted the Seattle Seahawks in Week 4.
What channel is Los Angeles Rams vs. San Francisco 49ers on tonight?
The Rams vs. Seahawks matchup will be broadcast on Amazon Prime, which once again owns the NFL’s broadcast rights to “Thursday Night Football.” Al Michaels (play-by-play), Kirk Herbstreit (game analyst) and Kaylee Hartung (sideline reporter) will be on the call for the game.
NFL fans watching the game nationally will need to have an Amazon Prime subscription to access Thursday’s game. However, the NFL has an arrangement for the viewers in the local markets of each team – Los Angeles and San Francisco – to watch a simulcast of the game on local TV stations.
Below is a look at the local channels that will air the contest:
- Los Angeles: KTTV (Fox 11)
- San Francisco: KTVU (Fox 2)
Watch “Thursday Night Football” with a Prime Video subscription
2025 Los Angeles Rams schedule
Los Angeles Rams record 2025
- Los Angeles Rams: 3-1; tied for first place in NFC West.
2025 San Francisco 49ers schedule
San Francisco 49ers record 2025
- San Francisco 49ers: 3-1; tied for first place in NFC West.
2025 NFL team schedules: complete team-by-team schedule of games
Complete 2025 NFL regular season schedule: every team’s games, week-by-week
