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Lorenzo Musetti vs. Francisco Comesana Head-to-Head, Prediction and Betting Odds for ATP Shanghai Masters 2025 Round-2

Round of 64 action at the Masters-1000 in China.

No. 8 seed Lorenzo Musetti returns for another attempt at glory on Chinese soil, as he begins his 2025 Rolex Shanghai Masters campaign against Francisco Comesana. The 23-year-old retired during his quarterfinal encounter in Beijing, and will be hoping for a change of fortune in this Round of 64 vs the Argentine. The winner of this match will face either Luciano Darderi or Yunchaokete Bu in Round-3. Follow The Playoffs News and BetMGM to get all the fresh updates during the tennis season.

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Lorenzo Musetti vs Francisco Comesana Match Preview

According to rival Jannik Sinner’s coach, Lorenzo Musetti is rapidly improving on the hard and grass courts. The Italian is predominantly a clay court savant so far, and also won the Olympic bronze medal at Paris 2024. In the 2025 season, Musetti reached three semifinals and a final on the red dirt. Although he hasn’t been able to convert any of his noteworthy performances into a title run, the 23-year-old World No. 9 has notched an impressive 35-15 record so far. Coming into this event, Musetti has reached two quarterfinals (US Open & Beijing) and a final (Chengdu) in his last three competitions.

On the other hand, Francisco Comesana was a semifinalist at the Rio Open, and also completed two quarterfinal finishes in Bucharest and Gstaad. These results, paired with some reassuring outings on the ATP Challenger Tour, have given the Argentine a current ranking of No. 62 in the world. At the age of 24, Comesana is searching for his maiden career championship. The South American star is playing his first tour-level event since losing in the Round of 64 at the 2025 US Open. In Round-1 here in Shanghai, he defeated Blanchet 6-4 6-2.

Lorenzo Musetti vs Francisco Comesana Head to Head Record

Lorenzo Musetti leads the head-to-head against Francisco Comesana by 1-0. The Italian needed four closely contested sets to overcome his counterpart in the 2024 Wimbledon Round of 32.

EventRoundWinnerScore2024 WimbledonRound of 32Lorenzo Musetti6-2 6-7(4) 7-6(3) 6-3

Lorenzo Musetti vs Francisco Comesana Career Comparison

Lorenzo MusettiCategoryFrancisco Comesana9Current Ranking62167-126Career W-L Record22-2735-15YTD W-L Record18-202Career Titles00YTD Titles00Grand Slams0

Lorenzo Musetti vs Francisco Comesana ATP Shanghai Masters 2025 Prediction

When it comes to hard court statistics this year, Musetti holds a strong edge over Comesana. The Argentine has been able to land a mere 58% first serves, and fails to gain the necessary impetus to control the pace of the game. Musetti can alter his net clearance to great effect, and has a vicious backhand slice that draws a short return from his opponents. The Italian’s experience is likely to prevail in this Round of 64 encounter.

Prediction: Lorenzo Musetti in straight sets.

Lorenzo Musetti vs Francisco Comesana ATP Shanghai Masters 2025 Betting Odds

Musetti (1/3) is the favorite to advance to the Rolex Shanghai Masters 2025 third round over Comesana (9/4). According to the implied probability on the money line, the Italian has a 70% chance of winning in two or three sets. Given below is the full list of odds to keep an eye on (as per BetMGM):

  • Lorenzo Musetti Win: 1/3
  • Francisco Comesana Win: 9/4
  • Total Games >22.5: Evens
  • Total Games 10/13
  • Comesana +3.5 (Game Handicap): 23/25
  • Musetti Win -3.5 (Game Handicap): 41/50
  • Musetti to Win 2-0: 10/11
  • Musetti to Win 2-1: 12/5
  • Comesana to Win At Least 1 Set (No): 4/7
  • Total Games in Set-1 & Set-2 19/20
  • Tiebreaker in Set-1 or Set-2 (Yes): 10/3

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

(Image Credits: Geoff Burke, Imagn Images)

A passionate sports fan through and through, I am currently pursuing my MA in Global Sports Journalism. I specialise in tennis and football writing at The Playoffs News, and I have prior experience working at EssentiallySports and Sportskeeda. Born and raised in Bengaluru, India, sport was my safe space right from my childhood. After trying my hand at multiple sports and representing my educational institutions in cricket, badminton and table tennis, I found sports media to be my calling.

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