The Miami Dolphins (1-3) visit the Carolina Panthers (1-3) at Bank of America Stadium in Charlotte for a Week 5 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, October 5, including live updated odds and injury report news.
Panthers vs. Dolphins live odds, moneyline, over/under
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Panthers vs. Dolphins picks against the spread
Jon Hoefling: Miami Dolphins (-1.5)
There just doesn’t seem to be a world where Carolina can stop De’Von Achane.
Tyler Dragon: Miami Dolphins (-1.5)
Tyreek Hill’s season-ending knee injury is a devastating blow for a Miami team trying to get out of a 1-3 hole. The good news is the Panthers are a bad football team as well.
Richard Morin: Miami Dolphins (-1.5)
Sure, the Dolphins are 1-3, but the Panthers looked lifeless against the Patriots last week. Miami could have a breakout game.
Lorenzo Reyes: Miami Dolphins (-1.5)
This is another game I don’t like at all, because I don’t trust either team. The Panthers fluctuate wildly from week-to-week. Miami course corrected a touch, and they should ride their ground game, now that Tyreek Hill is out. I’ll tentatively back the Dolphins here.
Blake Schuster: Carolina Panthers (+1.5)
This feels pretty evenly matched on paper. I’ll give the nod to a home dog with an extra day of rest. Though I don’t think the loss of Tyreek Hill will impact the Dolphins as much as many expect it to.
Christopher Bumbaca: Carolina Panthers (+1.5)
Short week from Miami and a road contest that involves the first game plan without Tyreek Hill. Rebound spot for Bryce Young and the Panthers.
Panthers vs. Dolphins updated injury report
NFL Week 5 picks, predictions odds
USA TODAY NFL picks against the spread standings
NameWeek 42025 RecordBlake Schuster10-5-134-27-3Jon Hoefling7-8-133-28-3Tyler Dragon8-7-133-28-3Lorenzo Reyes5-10-130-31-3Chris Bumbaca6-9-130-31-3Jordan MendozaN/A24-22-2Richard Morin9-6-19-6-1
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