Detroit Lions at Kansas City Chiefs: predictions, betting tips and odds

Detroit Lions at Kansas City Chiefs date, start time & TV info
Date Sunday, October 12
Starts 1.20am (early Monday)
Venue GEHA Field at Arrowhead Stadium, Kansas City, Missouri
TV Sky Sports NFL
Last season’s AFC champions the Kansas City Chiefs lost only two games in the 2024 regular season but they already have three losses in 2025 after Monday night’s defeat in Jacksonville dropped them to a 2-3 record. They return home on Sunday night for the finale of 14 hours of live NFL action in a tremendous matchup against NFC powerhouses the Detroit Lions, who have won four games in a row since a Week One loss to the Packers.
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Detroit Lions at Kansas City Chiefs betting tips & predictions
Best bet
Detroit Lions +2.5
3pts 10-11 BoyleSports, Hills
Detroit Lions at Kansas City Chiefs preview
The Lions went to Arrowhead Stadium on the opening night of the season two years ago and beat the Chiefs’ 21-20 when the home side were attempting to celebrate their Super Bowl victory. They were party poopers that night but another Lions success on their return to Missouri would only add to the gloom hanging over the Chiefs.
Based on their performances over the first five weeks of the season, the Lions are clearly the better side and they have not really put a foot wrong since losing their opener on the road at Green Bay. The Lions have some defensive issues and will be without cornerbacks Terrion Arnold and DJ Reed, but the outlook is brighter for the visitors offensively.
The men from the Motor City are leading the NFL with an average score of 34.8 points per game, with quarterback Jared Goff top of the rankings for pass completion percentage (75.34).
The Chiefs’ offence has seriously regressed with QB Patrick Mahomes averaging just 6.9 yards per pass, while an interception cost them the game in Jacksonville. Tight end Travis Kelce has not been a factor this year and with Detroit operating at a higher level this season, the Lions look worth backing in receipt of a small handicap start.
Detroit Lions at Kansas City Chiefs betting odds
Sign up with Paddy Power to bet on Detroit Lions at Kansas City Chiefs. Here are the latest odds for Sunday’s game.
Match bettingOddsDetroit Lions11-10Kansas City Chiefs8-11HandicapOddsDetroit Lions +2.59-10Kansas City Chiefs -2.59-10
Total pointsOddsUnder – 52.59-10
Over – 52.5
9-10
Odds correct at time of publishing
Want more top sports betting advice? Make sure you take a look at Racing Post Sport’s tips for more of the latest picks from our experts.
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FAQs for Detroit Lions at Kansas City Chiefs
When is Detroit Lions at Kansas City Chiefs in the NFL?
The Lions visit the Chiefs in NFL Week Six on the night of Sunday, October 12.
Where is Detroit Lions at Kansas City Chiefs being played?
The game is taking place at GEHA Field at Arrowhead Stadium in Kansas City, Missouri, which has a grass surface.
What are the odds for Detroit Lions at Kansas City Chiefs?
The Lions are slight underdogs to win at 11-10 with the Chiefs the 8-11 home favourites. The handicap is set at 1.5 points.
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