Portland Trail Blazers at New York Knicks odds, picks and predictions

The Portland Trail Blazers (23-25) and New York Knicks (29-18) meet Friday at 7:30 p.m. ET from Madison Square Garden in New York, New York. Let’s analyze BetMGM Sportsbook’s NBA odds around the Trail Blazers vs. Knicks odds and make our expert NBA picks and predictions for the best bets.
Season series: Knicks lead 1-0, a 123-114 road win on Jan. 11 in which New York covered as a 5.5-point favorite and the Over (229.5) cashed. A trio of Knicks scored in the 20s: G Jalen Brunson (26), F OG Anunoby (24) and C Karl-Anthony Towns (20).
The Trail Blazers lost to the Washington Wizards 115-111 in their most recent outing Tuesday, failing to cover as a 7-point road favorite with the Under (232.5) cashing. G Shaedon Sharpe went off for 31 points on 11-for-20 shooting. Portland has lost 3 straight but won the previous 4 before that. The Blazers are 5-2 against the spread (ATS) over those 7 contests and are 27-21 ATS on the season.
The Knicks blasted the Toronto Raptors 119-92 Wednesday, covering as a 1.5-point road underdog. The Under (221.5) hit. New York again had 3 players top 20 points, led by G Mikal Bridges, who tallied 30 points on 12-for-15 shooting. The Knicks have won 4 in a row, covering in each. They are 23-23-1 ATS on the season.
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Trail Blazers at Knicks odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 11 a.m. ET.
- Moneyline (ML): Trail Blazers +225 (bet $100 to win $225) | Knicks -285 (bet $285 to win $100)
- Against the spread (ATS): Trail Blazers +7.5 (-110) | Knicks -7.5 (-110)
- Over/Under (O/U): 225.5 (O: -105 | U: -115)
Trail Blazers at Knicks key injuries
Trail Blazers
- F Deni Avdija (back) questionable
- G Scoot Henderson (hamstring) out
- G Damian Lillard (Achilles) out
- F Kris Murray (back) out
- C Duop Reath (foot) out
- G Matisse Thybulle (knee) out
- G Blake Wesley (foot) out
- C Robert Williams III (knee) questionable
Knicks
- G Josh Hart (ankle) questionable
- G Miles McBride (ankle) questionable
For most recent updates: Official NBA injury report.
Trail Blazers at Knicks picks and predictions
Prediction
Knicks 112, Trail Blazers 107
PASS.
Avoid this play. The Knicks (-285) are far too expensive a play here, but they should win at home.
BET TRAIL BLAZERS +7.5 (-110).
The Knicks have struggled at The Mecca of Basketball, Madison Square Garden, since the new year. They are 3-4 ATS at home in 2026 and 6-8 ATS overall. New York has struggled offensively, scoring 113 points or fewer in 5 of its last 8 contests.
Portland has covered often as of late and is 2-1 ATS in its last 3 away games. It has gone 5-2 ATS across its last 7 games, scoring at least 111 points in 5 of those. Considering those trends, take TRAIL BLAZERS +7.5 (-110).
BET UNDER 225.5 (-115).
If there’s one way both sides are trending, it is the Under. The Trail Blazers have scored fewer than 100 points in 2 of their last 3 games and are 2-6 O/U across their last 8 contests.
The Knicks have gone Under in 6 straight performances and have allowed 110 points or fewer in all but one of those games. Considering those trends, back UNDER 225.5 (-110).
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