San Francisco 49ers at Tampa Bay Buccaneers: predictions, betting tips and odds

San Francisco 49ers at Tampa Bay Buccaneers date, start time & TV info
Date Sunday, October 12
Starts 9.25pm
Venue Raymond James Stadium, Tampa, Florida
TV Sky Sports NFL & Channel 5
Defeats for the Bills and Eagles last week meant that there are no teams with unbeaten records left in the NFL and two of the teams with a league-best 4-1 record go head to head in the NFC when the San Francisco 49ers visit the Tampa Bay Buccaneers on Sunday in Week Six.
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San Francisco 49ers at Tampa Bay Buccaneers betting tips & predictions
Best bet
Tampa Bay Buccaneers -3
3pts 10-11 general
San Francisco 49ers at Tampa Bay Buccaneers preview
The San Francisco 49ers are heading into what could be a key game in the NFC playoffs race against the Buccaneers with their starting quarterback Brock Purdy set to be ruled out again and back-up Mac Jones likely to play despite a knee injury. The Bucs have prevailed in some tight finishes already this season and they look to have caught another break by facing the hobbled 49ers this week.
San Francisco’s third string QB is the undrafted Adrian Martinez, who has never thrown a pass in the regular season, so 49ers head coach Kyle Shanahan will have his fingers crossed that Jones can recreate his excellent effort in last week’s 26-23 overtime win over the Rams.
The Bucs have their share of injuries too, but managed to overcome the Seahawks on the road last week despite missing starting running back Bucky Irving and wide receiver Mike Evans. Tampa Bay’s only loss was against Super Bowl champions the Eagles and the 49ers’ form has a more flimsy look to it, with each of their four wins coming by five or fewer points.
The Californian outfit’s defence has been poor and even in last week’s win they gave up 389 passing yards. With wide receivers Jauan Jennings and Ricky Pearsall still bothered by injuries and tight end George Kittle sidelined for at least one more week, the 49ers could struggle to keep pace with the free-scoring Buccaneers, whose QB Baker Mayfield has formed a dangerous connection with rookie receiver Emeka Egbuka.
San Francisco 49ers at Tampa Bay Buccaneers betting odds
Sign up with Paddy Power to bet on San Francisco 49ers at Tampa Bay Buccaneers. Here are the latest odds for Sunday’s game.
Match bettingOddsSan Francisco 49ers5-4Tampa Bay Buccaneers8-13HandicapOddsSan Francisco 49ers +39-10Tampa Bay Buccaneers -39-10
Total pointsOddsUnder – 47.59-10
Over – 47.5
9-10
Odds correct at time of publishing
Want more top sports betting advice? Make sure you take a look at Racing Post Sport’s tips for more of the latest picks from our experts.
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FAQs for San Francisco 49ers at Tampa Bay Buccaneers
When is San Francisco 49ers at Tampa Bay Buccaneers in the NFL?
The 49ers visit the Bucs in NFL Week Six on Sunday, October 12.
Where is San Francisco 49ers at Tampa Bay Buccaneers being played?
The game is taking place at Raymond James Stadium in Tampa, Florida, which has a grass surface.
What are the odds for San Francisco 49ers at Tampa Bay Buccaneers?
The Buccaneers are home favourites to win at 8-13 with the 49ers the 5-4 outsiders. The handicap is set at 3.0 points.
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